By Jean-Louis Santini (AFP) – 10 hours ago
ATLANTA, Georgia — Diabetics who seek to aggressively lower their blood pressure and cholesterol are not reducing their risk of a heart attack and could suffer negative side effects, a study released Sunday said.
The results of the landmark Action to Control Cardiovascular Risk in Diabetes (ACCORD) clinical trial appear to repudiate years of medical advice for type-2 diabetics who face a high risk of heart attacks, stroke or death from cardiovascular disease.
"This information provides guidance to avoid unnecesarily increasing treatment that provides limited benefit and potentially increases the risk of adverse effects," said Susan Shurin, acting director of the National Heart, Lung and Blood Institute at the National Institutes of Health, ACCORD's primary sponsor.
The study, presented here at the 59th annual conference of the American College of Cardiology, followed 10,251 type-2 diabetics between the ages of 40 and 79 for an average of 10 years.
All participants joined the study with an especially high risk of cardiovascular disease.
The study sought to evaluate the effects on heart disease in diabetics of aggressively lowering blood sugar or blood pressure and lowering bad cholesterol while increasing good cholesterol.
All participants were enrolled in the blood sugar control trial, with some also assigned to the blood pressure trial and others assigned to the cholesterol treatment.
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